Physicians like Sir Charles Locock hypothesized that sedative drugs might calm overactive brain activity, a theory he confirmed by treating seizures with a medication called potassium bromide.

像查尔斯·洛士这样的医生假设镇静药物可能会平息度活跃的大脑活动，他通使用一种叫做的药物治疗癫痫发作证实了这一理论。